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A True Rock Star of Science

Written by Andrew Doerfler for


Besides being a respected geneticist, Dr. Rudy Tanzi has played with Aerosmith, just written a book with Deepak Chopra titled Super Brain, and will host a PBS special.


It was 2009 when Dr. Rudy Tanzi was asked to appear in a GQ magazine photo shoot for a campaign called “Rock Stars of Science.” The shoot, organized by the Geoffrey Beene Foundation, was aimed at raising awareness of scientific research by matching accomplished researchers with famous musicians. Tanzi, who heads Massachusetts General Hospital’s Genetics and Aging Research Unit and teaches neurology at Harvard Medical School, was paired with a fellow Bostonian, Aerosmith guitarist Joe Perry.


“After the shoot, I was talking to Joe, and I said that actually I play,” Tanzi said. “He said we should jam some time.”


Three years later, Tanzi really is a rock star of science. He recorded organ tracks for Aerosmith’s just-released new album, “Music From Another Dimension!,” he co-wrote the book “Super Brain” with physician and mind-body expert Deepak Chopra, and he adapted the book into a PBS special, which he also hosts in a Carl Sagan-like manner. Both “Music From Another Dimension!” and the book “Super Brain,” which offers techniques to use your brain most effectively, went on sale this month. The book hit No. 7 on The New York Times Hardcover Advice & Misc. bestseller list, while the record debuted at No. 5 on the Billboard 200. The television special will begin airing nationally on Saturday.


Tanzi, 54, is best known for his work on discovering genes linked to Alzheimer’s disease. He acknowledges that people may find it strange that he’s hanging out with rock stars or collaborating with Chopra, whose holistic, speculative approach to medicine and science has prompted criticism from more hard-line scientists. But both projects represent Tanzi’s longtime interests. Besides, he said, he tries not to worry too much about seeking approval, especially at this point in his career.


“The need for external validation sucks more energy out of you than probably anything else,” Tanzi said while seated in his Charlestown office, a space adorned with various awards for Alzheimer’s research, as well as a photo of him at the piano with his daughter. “It’s easy for me to say because I’ve already made it where I want to be academically. Would I be doing these things if I didn’t have tenure and an endowed chair? Probably not.”


Tanzi, who lives in Cohasset with his wife and daughter, has been balancing his scientific pursuits and his creative endeavors for decades. He’s been a musician since he was a boy in Rhode Island, first picking up the accordion before moving on to organ, piano, and harmonica. By 1980, he was performing in a band five nights a week while researching Huntington’s disease at Harvard during the day.


But his path to performing on the Aerosmith record didn’t really begin until the GQ photo spread.


That led Tanzi to play concerts for the Rock Stars of Science campaign with Perry and National Institutes of Health director Francis Collins, who plays guitar and had also appeared in the GQ shoot. Earlier this year, Perry invited Tanzi to appear with the Joe Perry Project at Muhammad Ali’s 70th birthday party and on “The Tonight Show With Jay Leno.” When working on the upcoming Aerosmith album, Perry felt the track “Something,” a slow, bluesy number, called for some of Tanzi’s Hammond B3 organ playing to start it off.


“He’s easily the best Hammond player I’d ever heard face to face,” said Perry, who sings lead vocals on “Something,” while Steven Tyler steps back to man the drums.


Perry said the work ethic Tanzi developed over years in the lab applies perfectly to music.


“Whether you feel like it or not, or feel inspired or not, you have to get in there and do the work,” Perry said. “Sometimes you don’t get anything. The only way you’re going to get it is if you keep trying, and that’s the same pattern that he does with science.”


As strange as it seems for a renowned genetic researcher to end up playing on a new album with one of rock’s all-time bands, Tanzi expects colleagues to react to his collaborations with Chopra with just as much surprise. In addition to “Super Brain,” Tanzi and Chopra have co-written a series of contributions for the San Francisco Chronicle that speculate on the idea of a conscious universe, rather than one based on random occurrences.


The two first met, Chopra said, two years ago in, of all places, the men’s room at TEDMED, a health and medicine conference in San Diego where both were speakers. Chopra was pleasantly surprised to learn that a persistent researcher like Tanzi was open to a holistic view of science.


“He’s very cautious; he has to be,” Chopra said. “I go out on a limb.”


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Write Your Comment


Mirna Malave - December 15, 2012
Edna Perez - November 26, 2012
Deepak posting a picture of himself on HIS page for HIS friends is narcissistic behaviour. Freedom of speech but no freedom to post pictures of oneself especially on a platform called FACEbook? \r\n\nUnfollowing someone because they lost your respect but 2 months later you are commenting on the persons wall is ........... behaviour.\r\n\nLiking two of your own comments is ........... behaviour.
Jayes Vora - November 26, 2012
Ms. Falconer, I respect your opinion and I believe you should respect mine, I am far for being angry, but what I can tell you is that anybody who trashes religion and religious people like Mr. Deepak has done in multiple occasions, is what\'s really negative, people should have the freedom to believe and search for God any way they chose. And for your information, as you, I was a follower of Mr. Chopra, but the moment he started trashing religions, and religious people the way he did, he lost my respect and that of many followers. And, I am not advocating for any religion in particular, since I am not extremely religious. So, I suggest that you go back and research Mr. D. blog from a couple months ago, and read about his views on religion/religious people, and the disrespectful way that he conveyed the message, then you talk........on a higher note, in this country, I believe, we all have freedom of speech whether we agree or not. God bless always!!!
Edna Perez - November 25, 2012
I\'m sorry Mr Chopra, I just wanted to make you laugh!
Rebecca Mae Evans - November 25, 2012
I do have a harvard sweatshirt that was handed down for the brother of an old acquaintance?lol
Rebecca Mae Evans - November 25, 2012
Well said Lizzie! Thought provoking as usual Deepak. Your books talk to me personally. Love and light to all!
Ambika Mudhoo - November 25, 2012
in this world, we always have criticizers/judges/negative people etc
Diane Belair - November 25, 2012